What should be done if a dose of thyroid medication is missed?

May 14, 2025
The Hypothyroidism Solution™ By Jodi Knapp The Hypothyroidism Solution™ By Jodi Knapp Jodi has provided a stepwise guide in the form of The Hypothyroidism Solution to help you in regulating the levels of your thyroid in a better and natural way. Along with curing hypothyroidism, it can also care a number of other health issues experienced by people all over the world. No side effect due to this program has been reported so far. So you can follow this program without any financial as well as emotional risk.

What should be done if a dose of thyroid medication is missed?

If you forget a dose of thyroid medication, it’s always better to act, but not with a panic mode. This is what must generally be done:

1. Take the Missed Dose as Soon as Possible
If you remember the missed dose a few hours later, take it as soon as possible. But don’t ever take two doses at once to make up for a missed dose unless your doctor instructs you to do that.

2. Skip the Missed Dose if It’s Too Late
If it is nearly time for your next dose (i.e., several hours since the missed dose), it’s usually best to skip the missed dose and take the next one at the regular time.

Never double up on thyroid pills to make up for a missed dose, as this can create a toxic overdose and potential side effects like hyperthyroidism (too much thyroid hormone).

3. Call Your Doctor
If in doubt, or miss doses repeatedly, call your medical professional for advice. Your doctor can alter your dosage or provide you with a more personal strategy for skipped doses.

Consistency is also necessary with thyroid medication. Ongoing skipping of doses or not keeping the dosage schedule may undermine treatment effectiveness and potentially result in thyroid imbalances.

4. Monitor Symptoms
Monitor any changes in symptoms after a skipped dose. If you are sick or have hypothyroidism symptoms (e.g., weight gain, tiredness, depression) or hyperthyroidism symptoms (e.g., increased heart rate, nervousness, weight loss), it is important to report this to your doctor.

General Reminder: Thyroid medications are to be taken at the same time every day, preferably in the morning, on an empty stomach, and with a glass of water for best absorption.

Please let me know if you need more detailed reminders regarding thyroid medications or missing doses!

Food intake can influence the absorption of thyroid medication, particularly levothyroxine, which is the most common medicine for hypothyroidism (underactive thyroid). The below can influence one’s ability to absorb thyroid medication:

1. Timing of Food Intake
Empty Stomach or Food: Levothyroxine is generally recommended to be taken on an empty stomach, ideally 30 to 60 minutes prior to meals. This ensures that the medication is absorbed effectively, as food may result in interference with its absorption.

Post-Meal: When taken with food, especially with high-fiber diet, the absorption can be reduced. This is because food in the stomach has a tendency to decrease gastric emptying and also modify the effectiveness of drug absorption.

2. Specific Foods
Foods High in Fiber: Foods that are rich in fiber, such as bran, cereals, and some vegetables, can bind the drug and prevent its absorption. This can reduce the blood levels of the thyroid hormone, which may affect the efficacy of treatment.

Soy Food Items: Soy contains substances that inhibit the absorption of thyroid hormones. Soy items like tofu, soy milk, and edamame, if consumed close to the time of ingestion of thyroid medications, can affect its efficacy.

Cruciferous Vegetables: Even though they usually don’t affect absorption in small amounts, broccoli, cauliflower, and cabbage are rich in goitrogens that, if eaten in large quantities, interfere with thyroid function, especially if iodine intake is low.

Coffee and Calcium Foods: Coffee can decrease levothyroxine absorption, so it’s best to wait approximately an hour after taking the medication before having coffee. Calcium (in milk, supplements, and fortified foods) can also interfere with absorption, so it’s best not to take thyroid medication and calcium-containing foods or supplements simultaneously.

3. Medications and Supplements
Iron Supplements: Iron may reduce levothyroxine absorption considerably. If you are taking an iron supplement, it is advisable to separate thyroid medication and iron intake by at least 4 hours.

Antacids: Antacids containing aluminum, calcium, or magnesium may lower thyroid medication absorption. It is advisable to take them at other times than thyroid medication.

4. Stomach Acid
Low stomach acid will impact thyroid medicine absorption. Some conditions or proton pump inhibitor (PPI) use will cause the stomach to become less acidic, which can lead to decreased thyroid hormone absorption.

5. Consistency
It’s important to take thyroid medicine at the same time each day in the same situation (i.e., always on an empty stomach, same time, with the same foods), so that thyroid hormone levels will be consistently maintained.

Recommendations
Take levothyroxine in the morning, at least 30-60 minutes before a meal.

Wait at least 4 hours after taking thyroid medicine before consuming any calcium, iron, or antacid supplements.

Try to maintain a standard diet schedule to avoid variations in thyroid hormone consumption.

If you are concerned that food might affect the efficacy of your medication, it may be well worth sitting down with your doctor to obtain personalized advice in your specific situation.

Would you like guidance on ingesting foods while taking thyroid medication?

The Hypothyroidism Solution™ By Jodi Knapp The Hypothyroidism Solution™ By Jodi Knapp Jodi has provided a stepwise guide in the form of The Hypothyroidism Solution to help you in regulating the levels of your thyroid in a better and natural way. Along with curing hypothyroidism, it can also care a number of other health issues experienced by people all over the world. No side effect due to this program has been reported so far. So you can follow this program without any financial as well as emotional risk